Insights in Stem Cells is an international open access, peer-reviewed academic journal. The journal is dedicated to publish quality articles with an emphasis on basic, translational and clinical research on stem cell. The journal is a broad forum focusing on the studies of biology and applications of stem cell including animal models and clinical trials. Authors are invited to contribute articles in the form of original research, review articles, critical analysis, scientific investigation reports, case reports, technical notes, letter to the editor, and commentaries on scientific, ethical, social and economic importance with relation to stem cell research.
Insights in stem cell publishes articles that cover all aspects of Stem cell therapy, Stem cell transplant, Stem cell biology, Cancer stem cell, Therapeutic cloning, Neural stem cells, Somatic stem cell, regenerative medicine.
Submit manuscript send as an email attachment to our editorial office at [email protected] or https://www.imedpub.com/submissions/insights-stem-cells.html
Pluripotent stem cells are often termed true stem cells because they have the potential to differentiate into almost any cell in the body. Pluripotent, embryonic stem cells originate as inner mass cells within a blastocyst. These stem cells can become any tissue in the body, excluding a placenta. They have the potential to develop into any type of human cell.
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Insights in Stem Cells, Health Systems and Policy Research, Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology,Bioenergetics: Open Access, Anatomy & Physiology: Current Research, Journal of Hematotherapy and Stem Cell Research, Journal of Stem Cell and Regenerative Medicine, Stem Cells and Cloning: Advances and Applications.
Cells derived from a Fetus that retains the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells. The embryo is referred to as a fetus after the eighth week of development. Once a fetal stem cell has been harvested, it has the potential to live indefinitely in the laboratory. Fetal stem cells can be isolated from fetal blood and bone marrow as well as from other fetal tissues, including liver and kidney.
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Insights in Stem Cells, Gynaecology & Obstetrics Case report, Insights in Cell Science, General Medicine: Open Access, Bioenergetics: Open Access, Journal of Tissue Science & EngineeringCancer Cells, Cell Stem Cell, Molecular Cell, Trends in Cell Biology, Cell Research.
Stem cell technology is a rapidly developing field that combines the efforts of cell biologists, geneticists, and clinicians and offers hope of effective treatment for a variety of malignant and non-malignant diseases. The ability of tissue stem cells to integrate into the tissue cytoarchitecture under the control of the host microenvironment and developmental cues makes them ideal for cell replacement therapy.
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Insights in Stem Cells, Insights in Chest Diseases, Journal of Transplantation Technologies & Research, Journal of Pharmacogenomics & Pharmacoproteomics, Drug Designing: Open Access, Stem Cell Report, Molecular Biology of Cell, Molecular and Cell Biology, Stem Cells.
Embryonic stem cells are derived from totipotent cells of the early mammalian embryo and are capable of unlimited, undifferentiated proliferation in vitro. It is known as a blastocyst and has two parts i.e., trophectoderm and inner cell mass. Embryonic stem cell's properties include having a normal karyotype, maintaining high telomerase activity, and exhibiting remarkable long-term proliferative potential. Human ES cells measure approximately 14 μm
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Gynaecology & Obstetrics Case report, Archives of Medicine, Cloning & Transgenesis, Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Advanced Techniques in Biology & Medicine, Cell Death and Differentiation, Aging Cell, Molecular Biology of Cell, Molecular Cell Biology.
Cancer stem cells are a subset of cancer cells which play a key role in predicting the biological aggressiveness of cancer due to its ability of self-renewal and multi-lineage differentiation. CSCs are potentially of profound clinical importance. They establish the clinical relevance of breast CSC markers by profiling a large cohort of breast tumours in tissue microarrays using Immunohistochemistry.
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Archives in Cancer Research, Journal of Neoplasm, Journal of Carcinogenesis & Mutagenesis, Epidemiology: Open Access, Journal of Vaccines & Vaccination, Journal of Cell Biology, Stem Cell Reports, Cell Death and Differentiation, Aging Cells, Molecular Biology of the Cell.
Bone marrow is the soft, sponge-like material found inside bones. It contains immature cells known as hematopoietic or blood-forming stem cells. Bone marrow transplantation is a procedure that restores stem cells that have been destroyed by high doses of chemotherapy and/or radiation therapy. Bone marrow or stem cell transplants are used to treat some types of leukaemia or lymphoma, and myeloma.
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Spine Research, Health Science Journal, Journal of Blood & Lymph, Orthopedic & Muscular System: Current Research, Journal of Osteoporosis and Physical Activity, Stem Cell Reports, Cell Research, Molecular and Cellular Biology, Cancer Cell, Cell Stem Cell.
The endothelium is the thin layer of simple squamous cells that lines the interior surface of blood vessels and lymphatic vessels, cells that form the endothelium are called endothelial cells. The main function of endothelial cells is to provide a barrier between the blood and the rest of the body tissues. The endothelial cells act like a sieve, restricting the passage of large molecules, toxic substances and bacteria into the brain tissue while allowing necessary molecules like oxygen, enzymes and hormones.
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Cellular & Molecular Medicine: Open access, Acta Rheumatologica, Journal of Autacoids and Hormones, Journal of Clinical & Cellular Immunology, Bioenergetics: Open Access, Stem Cell Reports, Cell Research, Stem Cells, Seminars in Cell and Developmental Biology
The stem cell controversy is the consideration of the ethics of research involving the development, usage, and destruction of human embryos. The controversy centered on the moral implications of destroying human embryos. Many funding and research restrictions on embryonic cell research will not impact research on induced pluripotent stem cells allowing for a promising portion of the field of research to continue relatively unhindered by the ethical issues of embryonic research.
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Insights in Stem Cells, Insights in Biomedicine, Journal of Stem Cell Research & Therapy, Journal of Transplantation Technologies & Research, Translational Medicine, Journal of Molecular Cell Biology, Molecular and Cellular Biology, Journal of Cell Biology, Molecular Cell.
Hair follicles also contain stem cells, and some researchers predict research on these follicle stem cells may lead to successes in treating baldness through an activation of the stem cells progenitor cells. Stem-cell therapy led to a significant and visible improvement in follicular hair growth. New hair grew effectively using human pluripotent stem cells, cells derived from human embryos or human fetal tissue that can become any other cell type in the body.
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Archivos de Medicina, Medical & Clinical Reviews, Hair Therapy & Transplantation, Journal of Transplantation Technologies & Research, Journal of Pigmentary Disorders, Nature Cell Biology, Cancer Cell, Cell Stem Cell, Stem Cell Reports, Aging cells.
Stem cell therapy is the use of stem cells to treat or prevent a disease or condition. Bone marrow transplant is the most widely used stem cell therapy. Bone-marrow has been used to treat cancer patients with conditions such as leukaemia and lymphoma. Stem cell treatment protocols employ well-targeted combinations of allogeneic human umbilical cord stem cells, autologous bone marrow stem cells, and autologous adipose stem cells, and to treat the diseases.
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Insights in Medical Physics, Journal of Intensive and Critical Care, Journal of Allergy & Therapy, Journal of Cancer Science & Therapy, Cell Death and Differentiation, Stem Cell Reports, Molecular and Cellular Biology, Cell Research, Stem Cells.
Stem cell transplantation is the transplantation of multipotent stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. The two main types of stem cell transplants are autologous and allogeneic. It is a medical procedure in the field of hematology, most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia.
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Insights in Stem Cells, Insights in Cell Science, Journal of Transplantation Technologies & Research, Journal of Clinical and Experimental Transplantation, Tropical Medicine & Surgery, Molecular Cell Biology, Cell Research, Molecular and Cellular Biology, Aging Cells, Stem Cells.
Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function. Regenerative medicine also includes the possibility of growing tissues and organs in the laboratory and safely implanting them when the body cannot heal itself. Examples include the injection of stem cells or progenitor cells obtained through Directed differentiation.
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Archives of Medicine, Insights in Biomedicine, International Journal of Physical Medicine & Rehabilitation, Journal of Health & Medical Informatics, Journal of Nuclear Medicine & Radiation Therapy, Aging Cell, Molecular Biology of the Cell, Cell Death and Differentiation, Stem Cells, Stem Cell Reports.
Human embryonic stem cell are also known as a human pluripotent stem cell, one of the cells that are self-replicating, are derived from human embryos or human fetal tissue, and are known to develop into cells and tissues of the three primary germ layers. Human embryonic stem cell research is thought to have great potential in disorders in which cellular loss is known to occur.
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Neural stem cells are stem cells in the nervous system that can self-renew and give rise to differentiated progenitor cells to generate lineages of neurons as well as glia, such as astrocytes and oligodendrocytes. These cells hold great promise for neural repair after injury or disease. The potential source of neural stem cells for neural repair is through the mobilization of endogenous stem cells.
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Insights in Neurosurgery, Journal of Universal Surgery, Journal of Neuroinfectious Diseases, Journal of Neurology & Neurophysiology, General Medicine: Open Access, Stem Cells, Aging Cells, Stem Cell Reports, Molecular and Cellular Biology, Journal of Molecular Cell Biology.
Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues. An adult stem cell is an unspecialised cell that is capable of Long term renewal and Differentiation into specialised cell types. The primary function of adult (somatic) stem cells is to maintain tissue homeostasis by replenishing senescent or damaged cells. They are also known as somatic stem cells, they can be found in children, as well as adults.
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Insights in Stem Cells, Health Science Journal, Translational Medicine, Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Journal of Tissue Science & Engineering, Trends in cell biology, cell stem cell, molecular cell, journal of cell biology, cell death and differentiation.
The endocrine pancreas represents an interesting arena for regenerative medicine and cell therapeutics. One of the major pancreatic diseases, diabetes mellitus is a metabolic disorder caused by having an insufficient number of insulin-producing β cells. Replenishment of β cells by cell transplantation can restore normal metabolic control.
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Molecular regulation of embryonic stem cell fate involves a coordinated interaction between epigenetic transcriptional and translational mechanisms. It is unclear how these different molecular regulatory mechanisms interact to regulate changes in stem cell fate. A dynamic systems-level study of cell fate change in murine ESCs following a well-defined perturbation.
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Critical Care Obstetrics and Gynecology, Journal of Neonatal Studies, Cloning & Transgenesis, Gynecology & Obstetrics, Clinics in Mother and Child Health, Stem Cell Research and Therapy, Aging Cell, Stem Cell, Cancer Cells.
Author(s): María Vallet-Regí, Juan L Paris, Paz de la Torre, Victoria Cabañas M, Miguel Manzano, and Ana I Flores
Author(s): María Vicenta Camarasa